Based on a true story, The Girl in a Red Sweater is about a high school girl who suddenly goes missing in Lubbock, Texas, when she goes out on a date with one of her two boyfriends. Family members and friends launch a search for the girl but cannot find her. Soon, people are pointing fingers at one of the girl’s boyfriends as the culprit behind her disappearance. A reporter with the local newspaper soon begins digging into what happened to the girl.